The Role of Hormones in Fertility

Raising a family is an amazing experience. It is among the most amazing things that can happen in a relationship between a couple. The amount of hormones a woman’s body produces is one of the most crucial factors in getting pregnant. Hormones control whether the egg develops into a viable embryo and travels to the uterus, as well as whether the embryo finds a secure location within the womb to spend the next nine months gestating. Hormones have a major role in fertility, pregnancy, and the problems that many of our patients face.

At Imprimis IVF, a leading IVF treatment centre in Srinagar, we believe in extensive patient care and education. This blog explores the role of hormones in fertility and provides you with IVF literacy.

What are Hormones?

Hormones are necessary for the body to operate properly. More than 50 known hormones that regulate bodily functions and internal organ systems are found in human blood. These include metabolism, temperature control, and growth. Any deviation in the type or amount of hormones might lead to an imbalance in the hormones.

Because of the natural hormone fluctuations that take place during the menstrual month, each woman’s cycle is unique. Women’s fertility is significantly impacted by the complex interactions that exist among these hormonal networks. Maintaining appropriate hormone secretion and getting examined by the best IVF doctor at the best fertilization clinic is essential for treating female infertility.

Key Reproductive Hormones

Hormones in women naturally change during their menstrual cycle and every woman’s cycle is different. The intricate interactions among these hormone networks significantly influence women’s fertility.

A woman’s body has a complicated web of hormones that are involved in fertility and reproduction. The primary hormones that regulate the ovarian response hormones are progesterone and oestradiol, FSH and LH. Every hormone is essential to the menstrual cycle’s rising and falling phases.

Estrogen:

Many different tissues and organs are influenced by estrogens. Its primary mechanism of action is to induce cell proliferation in the ovaries, breasts, and endometrium. It is essential to the maturation of supplementary sexual characteristics. It encourages endometrial development during the menstrual cycle, preparing it for embryo implantation.

Progesterone:

Progesterone alters the uterine lining, which aids in conception. This enables a fertilized egg to adhere to it and begin developing into an embryo. During ovulation, progesterone begins to rise in order to prepare the uterus for the fertilization of an egg in an IVF and ICSI.

Follicle-Stimulating Hormone (FSH):

FSH or follicle-stimulating hormone is a hormone that is essential for both men’s and women’s reproductive processes. Having too little of either partner can cause problems with infertility. A female’s odds of conceiving and maintaining a pregnancy may be directly impacted by her FSH levels, which also have an impact on the quantity and quality of her remaining eggs.

Luteinizing Hormone (LH):

Luteinizing hormone or LH is important to the health of the reproductive system. The level of LH in the blood is important for couples who are having trouble getting pregnant or staying pregnant. An LH test is essential if you are thinking about IVF procedures.

Hormonal Imbalances and Fertility Issues

The first step to allowing yourself to take proactive steps for enhanced reproductive health is understanding hormone imbalances. It is crucial to speak with a healthcare provider if you are having trouble getting pregnant so they can look into any potential hormonal problems.

Your most effective tool is knowledge; treating hormone abnormalities is only one part of a more comprehensive approach to fertility. Recall that you are not walking this route by yourself. You can get assistance to help you overcome these obstacles. Remain knowledgeable, ask for help, and manage your fertility proactively.

Symptoms of a hormonal imbalance

Symptoms of a hormonal imbalance - Hormones

  • Absence or irregularity of periods
  • Seeing spots when not having a period
  • periods that are unpleasant or weighty
  • The body will see an increase in hair growth.
  • Unusual weight gain
  • constipation and diarrhoea

Individual differences in symptoms can be important. Women may occasionally have irregular vaginal bleeding, heavy or missing periods, pelvic pain, or other symptoms depending on the cause of their infertility. Talk to your doctor about any strange symptoms you experience. Even if you are not attempting to conceive, you should still get treatment for any underlying hormonal issues that some of these symptoms might indicate and getting your checkup done at a great fertilization clinic with the best fertility specialist is crucial for the future.

Diagnosing Hormonal Issues and Treatment Options

Suppose a woman has been regularly engaging in unprotected sexual activity with her partner for more than a year in an attempt to conceive. In that case, she may want to think about getting tested for fertility. After six months of attempting to get pregnant, a woman 35 years of age or older should think about getting tested for fertility. In order to treat infertility effectively and provide a couple with the best chance of becoming pregnant, fertility tests for women assist in determining the cause or causes of the condition.

Our skilled fertility doctors at Imprimis IVF, Ranked one of the best IVF clinics perform a thorough assessment that includes a thorough medical history, a physical examination, and blood tests to measure hormone levels.

For the treatment of fertility issues a thorough, integrated and accurate diagnosis of the underlying problem is required. The treatment options consist of the following:

  • Medicines
  • Hormone treatment
  • Surgery
  • Reproduction with assistance
  • In-vitro fertilization, or IVF
  • Zygote intrafallopian transfer, or ZIFT, and gamete intrafallopian transfer, or GIFT

Frequently Asked Questions

Q: Does infertility affect only women?

A: No. Either gender can experience infertility. Hormonal problems are just one of the many reasons why some women are infertile. But even men can experience infertility problems, such as low sperm count and not being able to conceive a woman.

Q: How to increase women’s fertility?

A: Frequent checkups can assist in identifying any underlying medical issues that may have an impact on a woman’s ability to conceive. Fertility can also be increased by leading a healthy lifestyle that includes frequent exercise, a balanced diet and stress management.

Q: How does estrogen make females feel?

A: Naturally, estrogen varies. However, mood swings or feelings of depression or anxiety may result from an estrogen imbalance. To assist in alleviating these side effects, doctors may recommend estrogen therapy.

Takeaway

We understand the emotional challenges of infertility and are committed to providing compassionate care and personalized treatment plans. helps you achieve your dream of parenthood. Our experienced fertility specialists can diagnose and treat a wide range of reproductive health problems, including uterine polyps. With advanced diagnostic tools and multiple treatment options, we can create a plan that meets your specific needs and increases your chances of success.

Located in the heart of Srinagar, Imprimis IVF Fertility Clinic is a ray of hope amidst the challenges of testicular atrophy and infertility. We offer personalized care and transformative fertility solutions. As one of the best IVF centres in Srinagar, our commitment to excellence is reflected in every aspect of our practice. At Imprimis IVF & Fertility Centre, we understand the importance of your dream of starting a family. Our experienced fertility specialists work closely with you to develop a customized treatment plan that is tailored to your needs.

The Future of Fertility Treatment

The field of fertility treatment is always changing and giving infertile couples hope. While traditional techniques like in vitro fertilization (IVF) have helped many people achieve their goal of becoming parents, cutting-edge technologies are on the horizon that might completely transform the field of fertility treatment.

The success rate and treatment experience for individuals looking to establish a family has improved significantly in recent years because of several advancements and trends in the field of fertility therapy.

We’ve all heard of IVF, ICSI, and a variety of other fertility therapies by now. The recent success rate of IVF has encouraged specialists to incorporate AI and continue developing innovative techniques to assist individuals in becoming parents.

Research and Innovation for Fertility Treatment

The main goal is to enhance the whole patient experience during reproductive treatment, regardless of the final result. Clinics must overcome major challenges in order to provide the highest quality of reproductive care. In order to give each patient the best care possible, doctors must make a complex series of clinical decisions that are crucial to successful IVF pregnancies.

It is acknowledged in the clinical setting that historically, funding for research and development related to women’s health and infertility has been inadequate. Therefore, fertility clinics in the private sector have mostly been responsible for recent breakthroughs. But lately, investors and tech entrepreneurs have been paying greater attention to the space many of them were inspired by their own experiences. Research and innovation on several challenges that contribute to infertility are still ongoing and a few of these major challenges millions of couples dealing with infertility face are:

Role of Artificial Intelligence in Fertility Treatment

 Artificial intelligence has lowered expenses, increased pregnancy rates and greatly enhanced in vitro fertilization. Unfortunately, it also brings up moral issues like algorithm bias and data privacy. Finding a way to balance these difficulties is still important for society and the medical community. AI is still a crucial tool in the ongoing effort to facilitate assisted reproduction and provide happiness to those desiring motherhood despite these obstacles.

By eliminating human subjectivity from the decision-making process and objectively classifying gametes, sperms, eggs and other essential things required for pregnancy according to quality, artificial intelligence has the potential to be revolutionary. But, the practice of fertilizing may limit the use of AI. The selection of sperm for intracytoplasmic sperm injection (ICSI), a procedure now carried out by embryologists, may not yield the greatest advantage from AI but on the other hand using regularly produced photos or time-lapse films, AI can also objectively evaluate and rank embryos, assisting in the decision of whether to transfer or freeze them.

AI has the potential to significantly change and advance numerous aspects of human existence, including medicine and, in particular, problems pertaining to infertility. The present difficulty with AI is that it uses various techniques and algorithms on various platforms. As a result, the population or clinic for which the platform is intended is now the only one for which AI algorithms are generally applicable. Put otherwise, the bare minimal requirements for its implementation have not yet been established in order to carry out the technology for the entire community.

Emerging Technologies in Fertility Treatments

IVF or in vitro fertilization, has seen a significant transformation in the last several years and is now a more viable option for infertile couples. This trend can be linked to ongoing innovation and research in reproductive medicine.

Artificial Intelligence:

Massive amounts of patient data analysis, including medical history, sperm quality, and embryo qualities, are being made easier by the development of AI systems. This can help with:

  1. enhanced choice of embryos
  2. Individualized care programs
  3. Embryo monitoring in real-time

Automated IVF Labs:

Two of the most exciting technological developments that could soon lead to universal access to IVF are automation and the downsizing of IVF laboratories. Nonetheless, the majority of the IVF process is still done by hand. With its revolutionary new IVF AI, practically all necessary steps can be automated in one device, potentially revolutionizing in vitro fertilization.

Enhanced IVF Procedures through Robotic Surgery:

In the future, robotic-assisted surgery could be utilized for procedures like egg retrieval, possibly lowering the risk of problems and speeding up patient recovery.

In Vitro Gametogenesis:

This emerging technology aims to create sperm or egg cells from stem cells. IVG may give couples experiencing infertility problems due to defective sperm or egg production some hope, even if it is still in its early phases.

Use of Technology in Fertilization

Recent developments in robotics and nanotechnology have led to an increase in the automation of intracytoplasmic sperm injection (ICSI). Thanks to this technology, clinicians can now analyze oocyte penetration in real-time and choose the finest sperm or embryo for a given circumstance. The growth of a healthy embryo has been made possible by the application of nanotechnology in the selection of appropriate sperm cells. Reproductive technologies have undoubtedly advanced significantly in recent years and are still growing and improving.

Numerous developments and trends in the field of fertility treatment, such as assisted hatching, preimplantation genetic screening and diagnosis, time-lapse imaging, and artificial intelligence, are contributing to higher success rates and better patient outcomes.

We encourage you to get in touch with the best fertility specialist at Imprimis IVF as the first step toward fulfilling your dream of becoming a parent if you are thinking about undergoing reproductive therapy. You have the highest chance of becoming pregnant and bringing a healthy baby to life with our skilled medical procedures. At Imprimis IVF, Sri Nagar, we work diligently and we are transparent about our costs and procedures and also provide flexible payment plans.

Schedule an appointment now and talk about a customized price for your unique set of treatment requirements!

Frequently Asked Questions

Q: At what point should I think about getting a fertility treatment?

A: It is advisable to see a fertility specialist if you have been trying to conceive for a year or six months if you are over 35 and have not been successful.

Q: What are the various fertility treatment success rates?

A: Success rates can differ according to age, the underlying cause of infertility, and the kind of treatment used. The Imprimis IVF experts in Srinagar will go over success rates based on your particular circumstances.

Q: What ethical issues are raised by new reproductive technologies?

A: New fertility technologies bring up ethical issues that should be carefully thought through. It’s critical to make sure these developments are applied morally and sensibly.

Why Choose Imprimis IVF Srinagar for fertility treatment?

We at Imprimis IVF Srinagar are aware of the psychological and physical impact that infertility has. To help you accomplish your dream of motherhood, our devoted team of fertility specialists is committed to offering individualized care and evidence-based therapies.

We provide a clear and cost-effective wide variety of reproductive services, such as IVF, ICSI, IUI, and innovative solutions. With the newest technology available, we guarantee the best success rates. We support open communication and patient empowerment during your therapy. Visit Imprimis IVF Srinagar and allow us to assist you in starting a family.

Secondary Infertility: Causes, Signs, Diagnosis & Treatment

What is Secondary Infertility?

When you are experiencing trouble getting pregnant after giving birth before, this is known as secondary infertility. Secondary infertility is characterized by a prior birth that did not happen with the help of medicine or fertility procedures such as in-vitro fertilization (IVF). On the contrary, the definition of primary infertility is the inability to conceive in a person who has never given birth.

How frequent is secondary infertility then? It could come as a surprise if you’ve previously had a child struggle with conception. That being said, many individuals and couples who are trying for more children are confronted with the difficulty of secondary infertility. 

Causes of Secondary Infertility

The same factors that contribute to primary infertility also lead to secondary infertility. These include age-associated impairments in fertility, hormonal disorders, blockages in the reproductive organs such as the uterus, fallopian tubes, or ovaries and lifestyle choices linked to weight gain, lack of sleep, stressful lifestyle, use of intoxicating substances. The causes of secondary infertility are similar for men. These include hormone abnormalities, lifestyle decisions and age-related concerns in fertility. However, some issues like testicular injury, genital infections or issues with ejaculation and sperm are particular concerns for men.

One of the most frequent reasons for secondary infertility is age. As a woman matures, her eggs become less plentiful and of worse quality, which raises her risk of miscarriage and lowers her chances of a successful pregnancy. A healthy woman has about a 15% chance of becoming pregnant every month by the age of 35. In contrast, men usually start to lose fertility around the age of 45. Research has indicated that older men may be more susceptible to genetic flaws in their sperm, increasing the likelihood of miscarriage, stillbirth, and the transmission of specific genetic diseases.

Another common cause of Male secondary infertility is frequently caused by low-quality semen, which includes low motility and sperm count. This refers to sperm that are ill-formed or not moving correctly, which makes it more difficult for them to move and fertilize an egg.

Signs of Secondary Infertility

signs of secondary infertility

The primary indicator of secondary infertility is the inability to conceive following the birth of one or more parents. After a year of trying to conceive, your doctor might suspect secondary infertility if you’re under 35. Having regular, unprotected intercourse is the definition of trying to get pregnant. After six months of regular, unprotected intercourse, your fertilization specialist may diagnose secondary infertility if you are over 35.

 Common signs of secondary infertility include:

  • Period irregularities or insufficient menstruation: These are examples of irregular menstrual cycles.
  • Period Pain: Excruciating pain throughout the menstrual cycle or during sexual activity.
  • Modifications in Sexual Function: Problems such as male erectile dysfunction or a decline in libido.

Diagnosis of Secondary Infertility

Diagnosis of secondary infertility

It’s critical to see the best fertility specialist if you suspect you may have secondary infertility to receive a proper diagnosis. What should you anticipate from a visit to the doctor? To diagnose secondary infertility, doctors typically start by getting information about a patient’s lifestyle and medical background. They enquire about the patient’s pharmaceutical regimen. Likely, your doctor will also do a physical examination.

  • Regular periods: Ensuring that ovulation happens regularly for women throughout their menstrual cycle.
  • Hormone testing: measuring blood levels of hormones such as progesterone, estrogen, and testosterone.
  • Sperm Analysis: Sperm count, motility, and structural characteristics are examined in semen.
  • Laparoscopy: A surgical procedure used to identify pelvic organ anomalies, primarily endometriosis.
  • Hysterosalpingography (HSG): This process uses X-rays to look for obstructions, anomalies, or irregularities in the uterus or fallopian tube.
  • Ultrasound: Reproductive organs can be examined with ultrasound technology.

Treatment Options for Secondary Infertility

A healthier diet, more exercise, and weight loss are all worthwhile adjustments to make if you’re trying to get pregnant. But you might want to visit a fertility doctor if, despite your best efforts, you haven’t been able to conceive after several months of trying. After the diagnosis has been done, If there is a concern related to pregnancy there are several treatment options for secondary infertility that are similar to those offered for primary infertility.

Our fertility specialists will work with you to determine which of the following options is best:

  • Fertility Medications: These are the primary therapies for infertility brought on by ovulation disorders. If ovulation is irregular or ceases, they can assist the ovaries in releasing an egg. Discuss your alternatives with your medical team. Figure out the advantages and disadvantages of every fertility medication by asking your medical professional.
  • IUI: The process of getting a pregnancy by intrauterine insemination (IUI) requires placing sperm into the uterus of the woman. The sperm sample is ready in our lab ahead of time. Increasing the amount of sperm injected into the uterus increases the likelihood that the egg will be fertilized.
  • IVF: Another assisted reproduction method is called IVF (In Vitro Fertilization), which includes ovarian stimulation, harvesting of eggs and sperm, fertilization, and embryo transfer. In our lab, intracytoplasmic sperm injection, or ICSI, fertilises the eggs.
  • Techniques for Retrieving Sperm: If your semen contains no sperm or you are unable to ejaculate, these methods can nevertheless harvest sperm. When assisted reproductive techniques are planned and sperm counts are low or irregular, sperm retrieval procedures may also be performed.
  • Injection of intracytoplasmic sperm (ICSI): This technique is applied in addition to the typical IVF process. One sperm cell is manually inserted into an egg for fertilization in IVF after the egg retrieval step. ICSI is frequently required to increase the success rate of in vitro fertilization (IVF) or to cure male factor infertility difficulties.

Frequently Asked Questions

Q: How Much Does IVF Cost?

A: The location, facility, and IVF procedure requirements all have a significant impact on the typical cost of in vitro fertilization. The average cost of an IVF treatment is between Rs 90,000 and Rs 1,50,000. The price may change based on the circumstances.

Q: How ICSI Treatment Is Not Like IVF?

A: ICSI IVF is a specific type of IVF used mainly for cases of severe male infertility treatments in which a single sperm is inserted directly into an egg. The ICSI treatment cost is higher than that of a typical IVF cycle due to this extra step.

Q: What Elements Affect the Cost of IVF?

A: The cost of IVF is determined by several variables, such as the clinic’s location, the medical team’s level of experience, the intricacy of the case and the need for extra treatments or services.

Q: How Can I Discover the Finest Reproductive Clinic?

A: When selecting the top fertility clinic, consider the variety of services provided, patient testimonials, staff qualifications, and success rates of the facility. It’s a good idea to look for the best fertility centre nearby because convenience to your home is another important consideration.

Imprimis IVF: Your Partner In Overcoming Your Challenges

Going through secondary infertility can be complicated and emotionally draining. Nonetheless, there is hope for couples who are having difficulty conceiving again because of improvements in fertility therapies and the accessibility of specialized fertility facilities.

Although it may be a difficult path, growing your family is possible with the correct assistance and medical knowledge. Our goal at Imprimis IVF one of the best IVF centres in Srinagar is to support you in not giving up your dream of becoming a parent by offering thorough care and support.

All You Need to Know About Preimplantation Genetic Testing

While trying to get pregnant can be a happy experience, it can also be difficult for some couples. Consider preimplantation genetic testing (PGT) if you’re considering in vitro fertilization (IVF) as a therapy option for infertility. With the use of this cutting-edge method, it is possible to screen embryos for genetic defects before implantation, which may improve your chances of becoming pregnant and giving birth to a healthy child.

Preimplantation genetic testing (PGT) finds genetic variations in embryos produced through in vitro fertilization or IVF procedures. Before embryos are inserted into the uterus, PGT is carried out. Reducing the likelihood of transferring an embryo with a particular genetic disorder or specific chromosomal abnormalities is the aim of paired-parent technology (PGT).

Understanding Preimplantation Genetic Testing

PGT is a collection of sophisticated genomic tests carried out on IVF-created embryos. These tests look for chromosomal abnormalities or single-gene problems by analyzing the genetic composition of the embryos. This knowledge can be very beneficial for couples that have:

  • A history of recurrent miscarriages
  • Irregularities of the chromosome
  • Genetic diseases they want to avoid passing on to their children

There are three types of genetic testing of an embryo before transfer:

1. PGT-A:

Preimplantation genetic testing for aneuploidy, or PGT-A, is a screening method used to detect chromosomal abnormalities in embryos, which are assumed to be the most frequent cause of IVF treatment failure. As an illustration, the most prevalent chromosomal condition that we are aware of that has an extra copy of chromosome 21 is Down syndrome. It is typically advised for older women over 35 who are trying to conceive. 

2. PGT-M:

When one or both genetic parents have known genetic abnormalities, preimplantation genetic testing for monogenic/single gene disorder (PGT-M) refers particularly to the process of testing an embryo to see if it too possesses the genetic problem. The PGT-M process offers an alternative to current post-conception diagnostic procedures, which often include the tough option of terminating the pregnancy if the results are unfavourable because only unaffected embryos are sent to the uterus for implantation. Right now, PGT-M is the only way to prevent having a kid impacted by a genetic condition before implantation.

3. PGT-SR:

It is a test used to distinguish between embryos that have additional or missing genetic material due to translocation or rearrangement (unbalanced) and embryos that have the proper amount of genetic material (balanced/normal). PGT-SR increases the likelihood of a healthy pregnancy following an IVF cycle and decreases the risk of a miscarriage, failed implantation, or having a kid with a chromosomal issue.

At Imprimis IVF, We can accurately identify balanced and normal embryos. This makes it possible to transfer embryos without chromosomal rearrangement carriers, avoiding the rearrangement’s transmission to subsequent generations. Schedule your appointment now!

The Preimplantation Genetic Testing Procedure

PGT begins with traditional in vitro fertilization (IVF), which involves retrieving and fertilizing eggs in a laboratory setting. The embryos are cultured until they reach a stage known as a blastocyst, which typically occurs on the fifth or sixth day following egg collection. At this point of development, certain cells are destroyed.

The genetic material (DNA) from the biopsied cells is then tested to see if the faulty gene exists in each embryo. After the cell biopsy, blastocysts are stored until the test results are ready. Once normal embryos have been discovered, they can be safely delivered to the uterus. Excess intact embryos are frozen for later use, whereas defective embryos are discarded. It is one of the most complex but also crucial infertility procedures.

Fertility doctors perform these procedures for two main reasons. One is to assess whether embryos have genetic abnormalities, which frequently cause failed implantation and miscarriage leading to unsuccessful IVF. The second goal is to identify embryos with genetic flaws that could result in a child with a fatal genetic abnormality or inheritable disorders like muscular dystrophy.

Embryos with such faults are not allowed to be put into the mother’s womb for a pregnancy. According to research, genetic mistakes in embryos are a major cause of both failed pregnancy and live birth. Couples interested in PGT testing should consult with an expert fertilization specialist to discuss available options.

The Cost of Preimplantation Genetic Testing

If you are considering using a fertility clinic, the majority of them can give you an idea of how much IVF pricing is decided for the PGT procedure. Some may provide PGT as part of a “package,” but make sure to examine the services provided by each reproductive clinic to make sure there aren’t any additional costs. Request a cost worksheet that details every stage of the PGT process from early pregnancy monitoring to pre-cycle services because calculating the cost of in vitro fertilization is crucial if you are on a budget.

Many factors vary from patient to patient when estimating the cost of having a child via PGT. In vitro fertilization is a must for all PGT patients to retrieve embryos for biopsy. Transferring an embryo or embryos that are not impacted by the known hereditary genetic disease for which it is at risk, is the aim of PGT.

The following are some variables that may affect PGT and IVF costs:

  • The required number of IVF cycles
  • Count of embryos to be tested and biopsied
  • Pattern of inheritance for the genetic illness
  • Technology required
  • The specific IVF clinic

Frequently Asked Questions about PGT

Q: What are the different types of PGT?

A: There are three types of PGT:

  • PGT-A: Preimplantation genetic testing for aneuploidy
  • PGT-M-Preimplantation genetic testing for monogenic disorders
  • PGT-SR-Preimplantation genetic testing for structural rearrangements
Q. Who can benefit from PGT?

A: PGT can help couples with-

  • A history of repeated miscarriages
  • Chromosome abnormalities
  • A family history of a certain genetic illness that they want to avoid passing on to their babies.
  • Women over the age of 35
Q: Does PGT ensure a successful pregnancy?

A: Normal PGT results do not guarantee a successful pregnancy or avoid miscarriage, This is a very common misconception. Embryos with normal PGT results of any type can still fail to implant or result in a miscarriage

Q: What is the average cost of IVF and PGT procedures?

A: The average cost of an IVF cycle in India ranges from ₹2.5 lakhs to ₹4 lakhs. The cost may vary depending on additional drugs, procedures (such as ICSI), and the type of clinic.

PGT testing typically costs between ₹25,000 and ₹50,000 per embryo. The number of embryos tested will affect the total cost.

Why Choose Imprimis IVF 

Imprimis IVF is a renowned IVF Centre in Srinagar that specializes in helping couples fulfil their dream of becoming parents. We provide a broad range of fertility services, including modern therapies such as IUI, IVF, ICSI, and more.

Imprimis IVF recognizes that cost can be a major concern for couples considering reproductive treatment. We attempt to provide fair pricing and various payment choices for PGT as well as IVF packages, We try to keep IVF treatment charges as economical as possible. Please contact our staff to get a personalized price on PGT and IVF.

Schedule your appointment and get a consultation from the best IVF doctor available at our facility!

Hyperspermia: Symptoms, Causes and Treatment

Hyperspermia is a rare disease that affects male fertility. According to a study, about 4% of men have experienced this disease. More than half of the world’s population does not know about Hyperspermia, but it exists. However, no real or actual scientific research has been stated on this.

Hyperspermia can affect adult men of any age. It is important to note that although this condition can cause concern, Hyperspermia is not usually associated with serious health problems. but, it is important to consult a doctor to rule out any medical conditions or complications.

Hyperspermia is not a fatal or deadly condition, but it can still reduce the chances of pregnancy. It is important to get information on this topic so that all risks, such as infertility, can be avoided in the future. This article will help you learn more about male reproductive health.

What is Hyperspermia?

This condition is the opposite of Hypospermia, where a man produces less sperm than normal.

Hyperspermia is a condition in which a man produces more sperm than usual. Semen is the liquid that a man ejaculates during orgasm. It contains sperm and fluid from the prostate gland. Get yourselves expert treatment at fertility clinics.

The average volume of semen ejaculated ranges between 2 to 6 ml. If the semen quantity of a man goes beyond 6.3 ml, then he is said to be affected by Hyperspermia.

Symptoms of Hyperspermia

Symptoms of Hyperspermia

Hyperspermia is a condition in which a man produces more sperm than normal. It is produced by Seminal fluid which is a fluid that contains sperm that helps in reproduction. The prostate glands of the testicles produce this sperm. During Hyperspermia, a larger-than-normal amount of sperm is produced. This condition may not cause health problems but may affect fertility.

The main symptom of Hyperspermia is more sperm than usual. A man who has had Hyperspermia all his life may not realize that his sperm volume is high. Others may notice an increase in sperm volume, which may be a sign to see a doctor for a diagnosis. However, many people with this condition have no other symptoms and may never know they have it.

Some common signs of Hyperspermia may include:-

  •  Painful ejaculation
  • Anxiety about sexual performance
  • Dizziness after sex
  • Weakness or fatigue
  • Pressure in the pelvic area
  • Semen yellow or cloudy
  • Enlarged and swollen testicles

What are the Causes of Hyperspermia?

Doctors don’t know exactly what causes Hyperspermia. Some researchers suggest that it is related to an infection of the prostate that causes inflammation.

Some cases cause the problem of Hyperspermia and affect fertility. Men have a lot of sperm and have less sperm than normal in their ejaculation. Thus, this leads to diluting the material, negatively affecting male fertility. However, a low sperm count does not mean that a man is infertile. A person with this condition still has a chance to have a baby. They can still look forward to parenthood because the condition does not affect fertility if the sperm count is high.

Another main reason is the gap during intercourse because it causes the problem of sperm accumulation. If you use a sexual stimulant or the pill, this is again a major cause of Hyperspermia. Regular use of the pill improves sperm yield and levels. According to professionals, it is believed that when the prostate gland is inflamed, it can also cause this unusual condition in men.

When Should You Consult a Specialist?

See your doctor if you are concerned that you are producing too much sperm or if you have been trying to get your partner pregnant for at least a year without success and get your condition diagnosed. Your doctor will start with a physical exam. You will then have infertility tests to check your sperm count and other fertility measures.

Hyperspermia Tests

These Tests may include:

1. Sperm Analysis

You take a sperm sample for testing. This can be done either by masturbating into the cup or by pulling the cup out during sex and ejaculating inside. The sample goes to the laboratory, where a technician checks the sperm counter quantity, movement, and quality.

2. Hormone Tests

A blood test can determine whether you produce enough testosterone and other male hormones. Low testosterone can also cause infertility.

3. Ultrasound Tests

You may have an ultrasound of the testicles or other parts of the reproductive system to look for problems that may contribute to infertility.

Does Hyperspermia Require Treatment?

Hyperspermia is a condition that usually does not require treatment until it causes serious health problems related to conception. However, precaution is important, so it is recommended to refrain from using pills or drugs to increase sexual performance. If ejaculation causes problems, it is always wise to consult a urologist.

You do not need to treat Hyperspermia. Pregnancy only takes one sperm and one egg, why is a sperm count important? In short, it increases the chances of a successful pregnancy. When a man ejaculates over a woman, the chance that one sperm will reach and implant itself in the egg increases if there is more sperm in the semen. Normal semen contains 300 million sperm per mm.

However, if you’re facing symptoms that are affecting your normal functioning, you must consult a professional. Our expert faculty at Imprimis IVF are there to guide you at every step.

Do You Want to Know More? Get in Touch with Imprimis IVF Fertility Clinic

The success of achieving pregnancy with a low sperm count depends on the personal health of you and your partner. If you decide to start a family, there are many options available to you, such as adoption, IVF, or lifestyle changes to try to conceive. Your first step is to talk to a doctor who can help evaluate your sperm count and other factors related to fertility before making any plans for the future.

Located in the heart of Srinagar, Imprimis IVF & Fertility Centre is a hope amidst the challenges of Hyperspermia and infertility. With a dedicated team of fertility experts and cutting-edge technology, we offer personalized care and transformative fertility solutions. As one of the best IVF centres in Srinagar, our commitment to excellence is reflected in every aspect of our practice.

At Imprimis IVF Fertility Clinic, we understand the importance of your dream of starting a family. So, our experienced fertility specialists will work closely with you to develop a customized treatment plan tailored according to your unique needs.

We are committed to supporting you every step of the way, from diagnosis to treatment and beyond, so you can realize your dream of starting a family. Contact Imprimis IVF & Fertility Centre Srinagar today and let us light the way to parenthood together.

Everything You Need to Know about Testicular Atrophy

Welcome to Imprimis IVF Srinagar. Our guiding principle is to maximize results and minimize costs. In this article, we shed light on a major problem that affects male fertility – testicular atrophy. We explore its causes, symptoms, diagnosis, and available treatment options to ensure you have the information you need to make informed decisions about your reproductive health.

Our precise and comprehensive approach makes treatment for infertile couples easier and less stressful. Let’s dive right into this informative and engaging discussion!

Male Reproductive System

The male reproductive system is complex and contains organs and hormones important to a man’s well-being. On the other hand, abnormalities such as testicular atrophy, where the testicles shrink, can seriously affect both general health and fertility. Testicular atrophy is a condition in which a man’s testicles shrink. The testicles are part of the male reproductive system. They are located in the scrotum, whose main task is to regulate the temperature of the testicles.

Temperature regulation is important because the testicles produce sperm, which need a certain temperature to stay healthy and live longer. When the environment cools, the scrotum contracts; when the surrounding area becomes warmer than optimal, the scrotum relaxes and expands. This causes differences in the size of your testicles – which is completely normal. However, it is a condition in which the testicles shrink more than the temperature-regulating function of the scrotum.

Understanding Testicular Atrophy:

Testicular atrophy is a narrowing or shrinking of the testicles, not the scrotum. This can be caused by injury, underlying conditions, or exposure. Testicular atrophy can seriously affect male fertility, but with the right medical intervention and support, it need not be a barrier to parenthood. By understanding the causes, identifying the symptoms, and seeking timely treatment, you can take proactive steps to overcome testicular atrophy and achieve your dream of having a family. Our fertility specialist provides you with personalized statistics based on your circumstances.

Symptoms of Testicular Atrophy:

Symptoms of Testicular Atrophy

If you are a male who has not yet reached puberty, your symptoms will be different than in older men. You may experience:

  • Lack of facial and pubic hair
  • If the penis is larger than normal

It is best to see a doctor if you experience these symptoms.

If you are an older man who has already gone through puberty, your symptoms will be different than younger men. You may experience some or all of the following:

  • Decreased sexual desire
  • Decreased muscle mass
  • Slow or no pubic hair growth
  • Soft testicles
  • Infertility

Whether you find you have it or not; If you have any of the symptoms listed above, consult your doctor for an accurate diagnosis. Now we will understand what causes testicular atrophy.

Causes of Testicular Atrophy:

Causes of Testicular Atrophy

There are several factors which can cause testicular atrophy, including:

1. Hormonal imbalance:

Fluctuations in hormone levels like decreased testosterone production in the body can contribute to testicular atrophy.

2. Varicocele:

In this problem, the veins in the scrotum get dilated and swollen which causes reduced blood flow and oxygen supply to the testicles.

3. Infections:

Certain infections for instance mumps or sexually transmitted infections can also become a major reason for testicular inflammation and subsequent atrophy.

4. Trauma:

Injury or trauma to the testicles during sports events or accidents may cause damage to the testicles and can trigger atrophy.

5. Medications and Treatments:

Several medications like chemotherapy and radiation therapy can affect your testicular health and may cause atrophy.

It is important to note that these are not the only causes of testicular atrophy. For an accurate diagnosis and treatment, it is important to consult a qualified doctor. so choosing the right infertility centre is essential!

Diagnosis of Testicular Atrophy:

If you think that you may have testicular atrophy, it is very important to see a doctor to get the correct diagnosis. So what can you expect from a doctor’s visit? Doctors usually begin the diagnosis of testicular atrophy by asking questions about a person’s lifestyle and medical history. They ask about the medications the person is taking. Your doctor will also likely perform a physical examination of your testicles for size, shape, texture, and strength as well.

Finally, the doctor may order additional tests to determine the cause of testicular atrophy. Possible tests include:

  • Testicular ultrasound to look for abnormalities and circulation
  • Blood test to look for signs of infection
  • Swan or urine test to check for sexually transmitted infections
  • Hormone level tests
  • Sperm analysis to assess sperm quality
  • Testicular ultrasound to visualize testicular structure

These tools and methods are used to detect testicular atrophy. Now let’s have a look at the available treatment options.

Treatment Options for Testicular Atrophy:

Treatment of Testicular Atrophy

If a person finds out that they suffer from testicular atrophy early and receives treatment as soon as possible, the shrinkage and damage can be reversed. Some conditions, such as testicular torsion, require immediate treatment to prevent permanent damage to the testicles.

The underlying cause of testicular dystrophy determines the type of treatment. Treatment and early diagnosis can help reverse narrowing.

Several treatments are available:

  • Hormone Replacement Therapy: This treatment helps reduce the effects of hormonal imbalance on testicular atrophy and helps restore testicular function to normal levels.
  • Antibiotics and Antiviral Drugs: Some drugs can fight invaders and prevent damage caused by infections. Many patients feel relieved after taking antibiotics as they prevent the risk of surgery.
  • Surgery: Surgical treatment might be important in some cases as it can improve circulation and possibly reverse a varicocele or testicular torsion atrophy.
  • Lifestyle Changes: Minimising the consumption of alcohol, managing stress levels and controlling weight gain can play a crucial role in helping to improve testicular health.

If you want to treat this issue, get in touch with Imprimis IVF Srinagar, our experienced doctors will guide you through the process in full detail.

Imprimis IVF: Helping You Overcome Fertility Problems 

Testicular atrophy is an extremely serious problem for male fertility. But a diagnosis doesn’t have to be the end of your child’s planning journey. Imprimis IVF, a top IVF fertility centre, offers advanced analysis, personalized treatment plans, and comprehensive procedures such as IVF and ICSI to help you achieve your dream of becoming the parents that you want to be.

Located in the heart of Srinagar, Imprimis IVF Fertility Clinic is a ray of hope amidst the challenges of testicular atrophy and infertility. We offer personalized care and transformative fertility solutions. As one of the best IVF centres in Srinagar, our commitment to excellence is reflected in every aspect of our practice. At Imprimis IVF & Fertility Centre, we understand the importance of your dream of starting a family. Our experienced fertility specialists work closely with you to develop a customized treatment plan that is tailored to your needs.

We are here to support you every step of the way, from diagnosis to treatment and beyond, so you can dream about starting your family.

Solving these issues can be quite difficult, but don’t worry. Our team of experienced professionals, counsellors, doctors, and staff at our best infertility centre will make sure you feel comfortable throughout the procedure. You can visit here to study the proper guidelines for the procedure.

Freezing of Eggs, Embryos, and Sperms: All You Need to Know About Cryopreservation!

The ability to freeze embryos has emerged as a powerful tool. This process, known as cryopreservation, offers individuals and couples a chance to defy the traditional biological clock, allowing them to preserve their fertility for a future pregnancy. The chance to delay parenthood is a relatively new phenomenon.

Medical advances such as cryopreservation, freezing and storing gametes and embryos for later use, allow individuals and couples to control their family planning schedules. This article introduces the world of cryopreservation and explores its applications, benefits, and considerations.

Why is Cryopreservation an Emerging Trend?

Cryopreservation is no longer a futuristic concept but an established medical practice. Infertility centres in and around the world are interested in freezing eggs, sperm, and embryos.

Social factors such as higher education, career aspirations, or simply a desire to find the right partner lead people to preserve their fertility for a future pregnancy. The decision to freeze eggs, sperm, or embryos is quite, personal.

As a process, cryopreservation is an expensive process & medical insurance may not cover fertility treatments, so you must consider your goals & discuss them thoroughly with your partner, before making this decision.

Why Should You Opt for Cryopreservation?

Why Should You Opt for Cryopreservation

You must be wondering, why cryopreservation has been an emerging trend suddenly & why is everyone talking about it. Let’s dive into some reasons:

1. Body Clock

As we age, our fertility naturally declines. Think of eggs and sperm as superheroes because they’re the strongest when they’re young. Cryopreservation allows you to freeze eggs and sperm at their peak, giving you a better chance of getting pregnant later.

2. Medical struggles:

Cancer treatment can be hard on the body, including our reproductive system. Cryopreservation offers hope because it allows you to freeze whole eggs or sperm before treatment so you can have a family after recovery.

3. Finding Your True Self

Gender reassignment can affect fertility. Cryopreservation allows transgender people to preserve their ability to have children before hormone therapy or surgery.

4. Waiting for the right time

Maybe you’re busy building your career or haven’t found the perfect partner yet. Cryopreservation gives singles and couples the flexibility to freeze eggs, sperm, or even embryos so they can start a family when they are ready.

Does Freezing Damage Embryos?

A persistent question often arises: Does freezing harm embryos? The answer is that, like many things in science, it is not a simple yes or no.

Cryopreservation is a time- and temperature-sensitive process, and while the technology has continued to advance, there are inherent risks. Freezing can damage embryos, and thawing them later can also damage them. If multiple embryos are frozen, some or all may not survive the process, so choosing the right infertility centre is essential!

What is the Process of Cryopreservation?

Process of Cryopreservation

Imagine taking a break from planning your baby! This is what cold storage does. Here’s a simplified version:

1. Freezing Eggs

Think of it like putting eggs on ice. Doctors will give you medicine to make your ovaries produce more eggs. They then remove the eggs quickly and easily. Before storing them in a very cold freezer with a special antifreeze, they make sure they won’t be damaged by freezing.

2. Freezing sperm

It’s pretty simple. You provide a sperm sample and the clinic adds a special “antifreeze” to protect it. It then goes into the same ultra-cold freezer as the eggs.

3. Embryo freezing

It’s like putting in a little miracle. Doctors fertilize eggs with sperm in the laboratory and create embryos. These early embryos receive the same antifreeze treatment and super cryopreservation as eggs and sperm.

How Long Can Embryos Be Stored?

Imagine putting your family planning on hold for ten years! You can do this by freezing embryos. Most clinics recommend keeping them in the freezer during this time to give you flexibility. But here’s the great part: ten years is not a deadline. If you need more time, you can extend the storage.

If you want to preserve your eggs, sperm, or embryos, get in touch with Imprimis IVF Srinagar, our experienced doctors will guide you through the process in detail.

What can be Done in the Case of Separation from the Partner?

Embryos are created from sperm and egg. Therefore, sperm and egg providers must agree separately on the conditions of storage of embryos. Both the female as well as male partners (unless donor eggs or sperm are used) must complete a special consent form expressing their wishes regarding the use of the stored material.

Embryos can only be used if both male and female partners agree to the intended use. It’s also important to agree on what you want to do with the embryos if one of you faces mortality.

Going through these problems might be quite overwhelming, but don’t worry. The experienced team of professionals, counsellors, doctors, and staff at our infertility center will make you feel at ease. You can visit here to study the proper guidelines for the procedure.

Understanding the Risks & Benefits of Cryopreservation

Cryopreservation is like all medical procedures, It has its own considerations. Although freezing and thawing techniques have become increasingly successful, there is always the possibility that cells or embryos won’t survive the process. Also, cold storage and high costs could also be a major factor. However, the benefits often outweigh the risks.

Cryopreservation offers an opportunity to preserve fertility and give individuals and couples more control over their family planning decisions and choosing the right infertility centre is crucial. Pregnancy success rates with frozen eggs, sperm, and embryos continue to improve which makes it a viable option for many people.

Frequently Asked Questions

1. Is cryopreservation right for me?

A consultation with a fertility specialist at the Fertility Center is essential. You can also contact us at 7678556881 and we can assess your individual situation and discuss whether cryopreservation is compatible with your family planning goals or not.

2. What is the success rate of Cryopreservation?

Success rates depend on factors such as the age of freezing and the reason for cold storage. Your fertility specialist at Imprimis IVF can provide you with personalized statistics based on your circumstances.

3. What happens to unused frozen eggs, sperm, or embryos?

You always have the option to donate them to research or help another couple struggling with infertility.

Takeaway

Cryopreservation is a powerful technique that empowers individuals and couples to make informed choices about their reproductive future. By understanding the process, and its pros and cons, you can make decisions that align with your personal vision of parenting. We at, Imprimis IVF Srinagar, are dedicated to delivering exceptional results at our infertility centre and keeping the candle of hope burning for many people.

What are Uterine Polyps? What are the Treatments Available?

What are Uterine Polyps?

Uterine polyps are small tumours that form on the lining of the uterus, the place where a fertilized egg implants during pregnancy. Although they are usually harmless, they can cause discomfort and sometimes affect fertility. Uterine polyps occur when endometrial tissue grows excessively. Polyps are attached to the endometrium by thin stalks or broad bases that extend into the uterus.

Polyps are round or oval and range in size from a few millimetres (the size of a sesame seed) to several centimetres (the size of a golf ball) or more. You may have one or more polyps. Uterine polyps are usually not cancerous, but they can cause problems with menstruation, periods, or childbirth. This article explains everything you need to know about uterine polyps, including causes, symptoms, and treatment options. This is especially useful for women who are concerned about their reproductive health.

What Causes Uterine Polyps?

Doctors are not exactly sure what causes uterine polyps, but a few things may play an essential role. One is hormonal imbalance, especially excess estrogenNormally, estrogen helps the endometrium grow each month. Progesterone, another hormone, balances things out by preventing excessive growth of the lining. If there is not enough estrogen or progesterone, the lining can overgrow and form polyps.

Uterine polyps are sometimes asymptomatic, meaning they don’t cause symptoms. For this reason, many people with uterine polyps may never receive a diagnosis. Research does suggest that polyps are more common in certain populations. For instance, they’re more common in people who’ve gone through menopause than those who haven’t.

Certain diseases, such as polycystic ovary syndrome (PCOS), can also increase the risk of polyps. Other factors include ageing, being overweight, and using certain medications, such as tamoxifen, which is used to treat breast cancer.

What are the Symptoms of Uterine Polyps?

Uterine Polyps Symptoms

Uterine polyps don’t always cause problems, but some women experience symptoms that need attention. If you have any of these, it’s important to see a doctor to get a proper diagnosis.

Abnormal bleeding may be a sign of uterine polyps — especially if you’re postmenopausal. It can be alarming to have unusual bleeding, but most causes of bleeding like polyps are unrelated to uterine cancer. Early detection and treatment can help avoid complications, especially if you’re trying to get pregnant.

Let’s understand all the symptoms in detail:

1. Unusual bleeding

This is the most common symptom. You might have periods that last longer than usual and are heavier or bleeding between periods. Most periods last four to seven days. Normal menstrual cycles usually occur every 28 days but can range from 21 days to 35 days. Many people with uterine polyps have irregular periods.

2. Trouble getting pregnant

Polyps can make it harder for a fertilized egg to implant in the uterus lining.

3. Pelvic pain

Some women experience pain or discomfort in their lower abdomen, especially during their period or sex. This can be concerning and may lead to anxiety and uncertainty about the underlying cause.

4. Bleeding after menopause

If you’ve gone through menopause or stopped having periods and experienced any bleeding, it’s important to see a doctor right away.

How are Uterine Polyps Diagnosed?

Diagnosis of Uterine Polyps

Your fertility centre will review your medical history and ask about your symptoms. They may ask if you’ve ever had trouble getting pregnant. They might also run some pregnancy tests, including a pelvic exam. Additional tests and procedures may be needed to determine if the tumour is a polyp.

Doctors usually use several different methods to diagnose uterine polyps, including:

  • Review of your medical history: They will ask about your symptoms, illnesses, and medications you are taking.
  • Physical exam: This may include the pelvic area. where your doctor checks your uterus for possible abnormalities
  • Hysterosonography: During Hysterosonography, a care provider uses a thin, flexible tube (catheter) to inject salt water (saline) into the hollow part of the uterus. An ultrasound probe gets images of the inside of the uterus to check for anything unusual.
  • Imaging tests: A transvaginal ultrasound uses sound waves to create a picture of your uterus and ovaries.
  • Hysteroscopy: It is a procedure in which a thin, lighted tube is inserted into the uterus to see the lining directly.

Treatment of Uterine Polyps Options Available

Uterine Polyps treatment

The best home treatment for polyps depends on several factors, including their size, location, and whether they have symptoms. Your desire to have children is also important, so choosing an experienced fertility expert is crucial.

Here are some treatment options that can be beneficial-

1. Observation

For small, asymptomatic polyps, doctors may recommend waiting and watching them, especially in women who are menopausal or have no major problems.

2. Medications

Hormonal medications, such as progestins, can help shrink them. or prevent polyps from growing, often the preferred approach before surgery.

3. Uterine polypectomy

Your provider will likely be able to remove the polyp during a hysteroscopy. A hysteroscope allows your provider to insert tools that can be used to cut and remove polyps. The advantage of the hysteroscope is its accuracy. Your provider can see the polyp and remove it at the same time. They may then send the tissue to a lab to check for signs of cancer.

If the polyp is cancerous, you may need additional surgery. A hysterectomy, or surgery that involves removing the uterus, may be necessary in cases where the polyps contain cancer cells.

4. Surgery

If polyps are large or cause symptoms, surgery may be necessary. Procedures such as dilation and curettage (D and C) can remove polyps while preserving fertility. Choosing a qualified surgeon and a reputable fertility centre is crucial for such procedures.

Imprimis IVF Fertility Centre: Your Partner in Overcoming Challenges

Uterine polyps can affect fertility, but with early detection and proper treatment, you can overcome these obstacles and achieve. Healthy Pregnancy If you are experiencing infertility or symptoms of uterine polyps, Imprimis IVF Fertility Centre can provide care and effective solutions tailored to your unique situation.

We understand the emotional challenges of infertility and are committed to providing compassionate care and personalized treatment plans. helps you achieve your dream of parenthood.

Our experienced fertility specialists can diagnose and treat a wide range of reproductive health problems, including uterine polyps. With advanced diagnostic tools and multiple treatment options, we can create a plan that meets your specific needs and increases your chances of success.

Whether you are experiencing infertility, recurrent miscarriages, or other reproductive health issues, we are here to support youevery step of the way. You don’t have to walk this journey alone. Let Imprimis IVF fertility centre help you realize your dream of starting a family. Contact us today to schedule a consultation and take the first step toward a brighter future.

Signs and Symptoms of High Estrogen in Females – Causes & Treatment

Maintaining a proper balance of estrogen and other sex hormones is crucial for overall health. In females, high estrogen levels may result in weight gain, low mood, and severe premenstrual syndrome (PMS). While estrogen is primarily known as a female sex hormone, it’s also present in males, though in smaller amounts. Although estrogen levels naturally fluctuate, consistently high levels can lead to health issues, with effects varying between males and females. But in this article, we will focus only on high estrogen in females. 

Keep reading to discover more about the symptoms and causes of high estrogen levels in females.

What is the Meaning of High Estrogen?

Estrogen plays an important role in the human body by regulating key functions like the reproductive system. This hormone’s levels change throughout a person’s life, frequently coordinating with other important chemicals in the body. As a young person goes through puberty, estrogen rises significantly to spur sexual maturation. Working with progesterone, estrogen prepares the body so that it is ready for potential pregnancy later on. Its fluctuations signal important developmental stages from childhood to adulthood. While its levels and impacts vary over time, estrogen remains vital for overall health and well-being at every stage of life.

While a proper balance of hormones is necessary for overall health and well-being, too much or too little of certain hormones can potentially lead to difficulties. Specifically, when estrogen levels are higher than normal for an extended period, it can negatively impact reproductive processes within the body, bring about unpleasant sensations, and elevate the likelihood of developing select health problems. Further exploration into maintaining hormonal equilibrium is advised to avoid potential issues.

What are the Causes of High Estrogen?

Cause of High Estrogen in Females

 

There are a few ways that high estrogen levels can arise in the body. Sometimes, estrogen amounts increase naturally as part of the regular hormonal cycles. However, elevated estrogen may also develop due to certain prescription drugs or underlying medical problems. Some potential causes of high estrogen include:

  • Changes in hormones during menopause or the menstrual cycle can cause estrogen levels to fluctuate. The monthly cycle, in particular, experiences surges and drops in various hormones as an egg is selected and developed each month.
  • Some medications can raise estrogen in the body. It’s important to be aware of any drugs’ effects on hormone balance.
  • Certain underlying medical conditions may contribute to high estrogen. Pregnancy, obesity, ovarian or adrenal tumours, and liver disease from cirrhosis can all impact hormone production and removal from the bloodstream.
  • Aspects of one’s lifestyle and habits could play a role as well. Stress, ageing, body weight, and alcohol intake have all been examined for their potential ties to estrogen balance.
  • An imbalance between beneficial and harmful bacteria in the gut may slow the liver’s usual elimination of estrogen from the body. A disrupted microbiome could influence hormone processing.
  • An overgrowth of problematic intestinal bacteria or a lack of helpful gut microbes may hinder how quickly the liver breaks down and excretes estrogen. Proper gut health supports overall endocrine function.
  • Some perfumes and fragrance scents contain chemicals that disrupt typical hormone signalling in studies. More research is still needed, but certain synthetic compounds may disrupt balances.

What are the Signs of High Estrogen?

Signs of High Estrogen in females

 

Now that we understand what causes high estrogen in women let’s explore how the body responds to it. Here are some symptoms of high estrogen:

  • Abdominal bloating
  • Swelling or formation of breast lumps
  • Increased breast tenderness
  • Irregular periods
  • Decreased or absent sexual desire
  • Anxiety, panic attacks, or mood swings
  • Intensified premenstrual syndrome (PMS) symptoms
  • Fatigue, headaches, or tiredness
  • Weight gain

These signs illustrate what happens when estrogen levels are high in females. If you experience any of these symptoms, it’s wise to consult a doctor and undergo a check-up. Doctors typically recommend a blood test to assess estrogen levels in the body. There’s also a possibility of abnormally low estrogen levels, so it’s essential to get checked.

Diagnosing High Estrogen in Females

If your doctor suspects a hormonal imbalance, they’ll diagnose the cause from your symptoms and specific tests. If hormone replacement therapy (HRT) is causing your symptoms, they might suggest adjustments to your treatment plan.

How to Treat High Estrogen?

Treatment of high estrogen in females

 

Controlling estrogen dominance is crucial to prevent the medical complications mentioned earlier. Here are the most common treatments prescribed by doctors:

Lifestyle changes: 

Making lifestyle adjustments can effectively regulate estrogen levels in the body. Consider the following:

●      Reduce alcohol intake: Excessive alcohol consumption can hinder estrogen elimination, so it’s best to cut back.

●      Opt for healthy, nutritious foods: Eating fibre-rich foods and minimizing processed sugars aids in efficient estrogen breakdown by the liver. Avoiding high-fat meals can also be beneficial.

●      Manage stress: While avoiding stress entirely is challenging, learning to cope effectively can promote overall health. Minimizing unnecessary stress helps balance cortisol, estrogen, and progesterone levels.

Medications:

If you’re taking medications for cancer or other conditions, inform your doctor. They can adjust your treatment plan if any medications elevate estrogen levels, especially if you have conditions like cancer that can worsen with high estrogen levels.

Surgeries:

For females at high risk of ovarian or breast cancer, doctors may recommend oophorectomy, the surgical removal of both ovaries, to reduce estrogen production. Another option is ovarian radiation therapy, which halts ovarian function and estrogen production. These procedures do not increase cancer risk or spread.

Conclusion

Maintaining normal estrogen levels in both men and women is essential since this hormone controls multiple body functions. High estrogen levels may bring about a variety of symptoms such as weight gain, mood swings and abnormal menstrual cycles. The development of the factors, symptoms, and diagnosis of high estrogen must be a crucial step in the successful treatment. 

Lifestyle factors like limiting alcohol consumption and managing stress can help regulate estrogen levels, whereas medicines or surgical procedures may be required in certain cases. Prompt and comprehensive management of elevated estrogen levels will help to prevent the associated health conditions and guarantee good health. Frequent observation and engagement of healthcare professionals are central to the development of treatment plans specifically geared to suit each person’s needs.

What does Lupron do for IVF?

Medications are an integral part of the IVF treatment. Depending on the medical condition and other factors certain injections are administered to set the base for healthy development of the eggs. Lupron Injection is one such medication that is frequently administered before ovarian stimulation medications are given for a successful IVF treatment. 

Another drug, hCG or Human Chorionic Gonadotropin, is also widely used for egg maturation. But Lupron tops the list as it is better tolerated by the body. 

Lupron, lupride, or leuprolide acetate is a synthetic gonadotropin-releasing hormone agonist (GnRH-a). It is given to a woman at the start of the IVF treatment especially when there is a need to stimulate the ovaries to produce eggs in a controlled manner. Putting it simply, lupron helps control the development of eggs in the ovaries. 

Why is Lupron injection needed? 

Why is Lupron injection needed? 

To understand the need for Lupron injection we need to get down to the process of ovulation. 

  1. During menstruation, the hypothalamus which is a part of the brain releases gonadotropin-releasing hormone ie. GnRH. 
  2. This hormone sets the pituitary (another part of the brain) in motion to produce Luteinizing Hormone (LH) and the Follicle follicle-stimulating hormone (FSH) in the blood.
  3. These two pituitary hormones awaken the ovary every month to produce an egg for fertilization, secrete estrogen, and ovulate. 

So, when Lupron is injected into the body regularly it mimics the structure of GnRH and triggers the production of pituitary hormones FSH and LH. 

Initially, the pituitary glands fail to recognize the difference between GnRH and lupron (GnRH-a). However, with the regular administration of lupron, the pituitary glands become alert to this foreign element. As a result, the pituitary glands cap the production of both FSH and LH. The secretion of these hormones keeps on reducing as long as lupron injections are administered. This condition is termed pituitary down-regulation. In simple terms, it can be stated that Lupron helps reduce the secretion of these hormones

But why is it important to control the secretion of these hormones during IVF? Aren’t these hormones important for conception? 

Lupron is administered to the woman to limit the secretion of certain hormones to prevent early or premature ovulation during IVF. This helps in the development of multiple mature eggs in the ovaries. As soon as this condition is achieved the ovaries and the reproductive system are ready to respond positively to other medications that are administered for a successful IVF cycle. Ultimately, fertility experts gain more control over the ovulation timing, the egg retrieval process, and the implantation timing.

After embryo transfer, lupron ensures a healthy environment for its development free from any hormonal fluctuations. Hence, increasing the chances of success of the IVF cycle.

That’s just one part of the story of Lupron. It also has other significant roles to play in an IVF cycle like:
  • Leuprolide acetate is also administered to stimulate the ovaries. 
  • Also, it can be used as a trigger to assist with the complete maturation of the eggs for IVF. This is referred to as Lupron Trigger.
  • As the ovaries are also responsible for the production of estrogen and progesterone, Lupron indirectly helps regulate their secretion.
  • Lupron also finds application in the treatment of endometriosis, prostate cancer, and large uterine fibroids.
  • It plays a vital role in treating CPP which is central precocious (early) puberty in children.

The Lupron Protocol during IVF 

It is generally given daily for 2-3 weeks before the process of ovarian stimulation begins. However, the duration depends on your medical reports and your body’s requirements. The Lupron medication kit generally contains 14 injections (for 2 weeks) and 2.8 ml of Lupron in the form of Leuprolide acetate. Typically fertility specialists administer Lupron in three phases which are stated below: 

Phase 1

This phase generally starts one week before the ovarian stimulation process. The Lupron administration process begins as soon as the natural ovulation is completed. 

Phase 2

The administration of Leuprolide acetate will carry on. But in phase 2 the fertility experts cut down on the dosage in comparison with phase 1. 

Phase 3

This phase sets in 36 hours before the egg retrieval process. The dosage is discontinued before the hCG trigger shot is administered for final egg maturation. 

After some days of regular Lupron shots, FSH injections will also become a part of the IVF journey. You will have blood tests and ultrasound to monitor the entire process. 

Lupron Injection Side Effects

Lupron Injection Side Effects

More than anything else, keeping your stress levels in check is the first step towards a successful IVF cycle. However, experiencing side effects at the start of your IVF journey can quickly switch on the panic button. So, it’s always better to know all the common side effects associated with a medication to stay calm during IVF. Lupron injection is accompanied by several short-term side effects mentioned below: 

  • Erratic mood swings
  • General body aches
  • Upset stomach
  • Vaginal dryness
  • Headache
  • Vomiting and nausea
  • Hot flashes or night sweats
  • Edema
  • Weight gain
  • Body and face acne

The secretion of pituitary hormones is reduced to the same level as is witnessed during menopause (the time when a woman no longer has a monthly menstrual cycle). This means your body is pushed into a state of temporary menopause. So, you may have lighter or no periods during this phase. 

Other symptoms during the initial days include: 

  • Breast tenderness
  • Abnormal fluid retention
  • Joint pain
  • Fatigue
  • Dizziness
  • Anxiety
  • Tingling
  • Itching or swelling at the injection site
  • Decreased libido

These symptoms vanish once Lupron usage is discontinued. 

In case, you suffer from excruciating pain or any other extreme side effect consult with your gynaecologist at the earliest. 

How is Lupron Injection Administered? 

Lupron injection is generally administered into the fatty tissue present just below the skin either in the form of daily injections or as monthly intramuscular depot injections using a small needle. It can be administered by the medical expert at your fertility clinic or you can also do it yourself at home by following the below-mentioned steps: 

  • Wash your hands thoroughly and properly sanitize the surface where you will lie down. 
  • Take a clean syringe and fill the Lupron medication into it. Always ensure that there is no air in the vial containing the medication.
  • Select a spot on the abdomen about two inches from your navel.
  • Hold the syringe at an angle of 45 degrees from the injection site.
  • Empty the contents of the syringe quickly.

Lupron injection can also be administered on the outer region of a woman’s thigh. As far as storage of Lupron injections is concerned, they generally don’t require refrigeration. However, it is for the best that you strictly follow your doctor’s guidelines. 

Imprimis IVF advises you to visit your fertility expert to get your Lupron injections. Once you feel confident enough go for self-administration. Do not miss out on any of the steps mentioned above every time you take your Lupron dose. 

Frequently Asked Questions 

Does Lupron increase IVF success

Well not directly. IVF success rates depend on a plethora of factors. Some of them include the age of the woman, the quality of both the egg and the sperm, medical history, genetic conditions, and the expertise of your fertility specialist. However, proper and timely administration of Lupron will lay a robust foundation for other medications that play a vital role in IVF success rates. 

Is Lupron always given during IVF? 

No. Even though it is one of the best options available when it comes to ovulation regulation, Lupron is not always given during IVF. Doctors have a variety of options available in the form of agonists and antagonists to choose from and reduce the production of FSH and LH. hCG or human Chorionic Gonadotropin is seen as an alternative to Lupron. However, Lupron is seen as the better option because it is more tolerable than the former. 

Final Word 

IVF is a complex and delicate procedure in all dimensions. Not only the technology but also the medications administered before the treatment starts need to suit the woman’s body and meet some requirements for the treatment to proceed smoothly. 

Lupron is one such medication that doesn’t directly affect the success rate of IVF but sets the base for the treatment to proceed efficiently and offer promising success rates.

If you have any queries regarding Lupron, other medications or anything related to IVF treatment feel free to visit us at Imprimis IVF, Srinagar.